1 H PFG‐NMR Diffusion Study on a Sequence‐Defined Macromolecule: Confirming Monodispersity
نویسندگان
چکیده
منابع مشابه
An approach based on diffusion to study ligand-macromolecule interaction.
A new approach has been developed to study binding of a ligand to a macromolecule based on the diffusion process. In terms of the Fick's first law, the concentration of free ligand in the presence of a protein can be determined by the measurement of those ligands which are diffused out. This method is applied to the study of binding of methyl-orange to lysozyme in phosphate buffer of pH 6.2, at...
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15 صفحه اولBrownian Dynamics Simulation of Macromolecule Diffusion in a Protocell.
The interiors of all living cells are highly crowded with macromolecules, which differs considerably the thermodynamics and kinetics of biological reactions between in vivo and in vitro. For example, the diffusion of green fluorescent protein (GFP) in E. coli is ~10-fold slower than in dilute conditions. In this study, we performed Brownian dynamics (BD) simulations of rigid macromolecules in a...
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ژورنال
عنوان ژورنال: Macromolecular Chemistry and Physics
سال: 2019
ISSN: 1022-1352,1521-3935
DOI: 10.1002/macp.201900155